In 1996 Chris Clark invented the first SEO (Site Enhancing Oil) and named it ‘Synthol’. A quick phone call from brystol-Meyers, who hold the trademark rights on the ‘Synthol’ name, forced Chris Clark to change the name of his product to PumpNPose. However, the name of synthol was stuck with the bodybuilders.

The most popular now are Synthol/PumpnPose, Syntherol, EsikClean, Nuclear Nutrition Site Oil, Cosmostan and Liquid Muscle.

Synthol/PumpnPose is the original product. As such, it charges a lot of money and it’s the most expensive variant as it relies on it’s name to sell it – the cheapest found is $149.95. There must be a lot of fakes out there since the inventor of it, Chris Clark, charges a wholesale price of over $100 per bottle (and that’s for large quantity), so there’s no way that some outfits can retail it for $100. The only official distributor for PnP is www.meso-morph.com

Syntherol is my favourite simply because is the only one that I know of that is made by a real pharmaceutical company, so guaranteed sterile, plus it hurts less and the results seem to be better – don’t take my word for it, ask around! It’s the same formula as Synthol/PumpnPose, with added silica, which is a safe way to make the gains more ‘permanent’. It’s very refined, so it flows freely through a 28gauge needle, unlike the others which need as much as 21gauge needles to go through properly!
It’s also the number 1 best selling Site Oil in the world, so they must be doing something right! And Synthetek (the maker of Syntherol) is the only company to offer a double money back guarantee and they never had any complaints from any customer from anywhere in the world! By far my choice, plus, it’s cheap – $129.95. www.synthetek.com

EsikClean – same formula as Synthol, but it has colagen added. That makes it a very bad choice to use in my opinion. When you use site oils, the biggest problem is the formation of scar tissue. You don’t want any scar tissue build up when you use site oils. Scar tissue is colagen buildup due to the trauma caused to the muscle by sticking a needle in there. As such, I would not help the build up of scar tissue in the muscle by injecting colagen. So, that’s a bad choice. $100 per bottle www.synthol-direct.com Plus these are the people that counterfited Chris Clark’s PnP and Synthetek’s Syntherol, so one wonders how ‘genuine’ they are. Their associated websites are www.synthol.com, www.finalabs.com, www.zoelabs.com, www.pumpnpose.com, www.primolabs.com I strongly recommend that people stay away from them!

Nuclear Nutrition Oil – is a very good product, which works quite well. It’s exactly as Syntherol, plus the addition of a small amount of prohormones. I am not a big fan of prohormones due to the reason that they will give you more side effects than benefits. Also, because of the prohormones, you cannot import it into countries like Canada or Australia, where prohormones are illegal. Still a good product – $149.95 www.nuclearnutrition.com

Cosmostan is another one that I recomend that people don’t use. It has two anabolic steroids added to it. Because the SEO oil is a very long chain fatty acid, it will wrap itself around the steroid oil, as such not allow the steroid oil to be dissipated timely and for the body to assimilate the steroid. Also, both steroids contained in it are esterified, as such, they would have absolutely zero effect on localised growth as all esterified steroids have to travel to the liver first. Also, because of the steroids contained in it, it is illegal in most places in the world and women cannot use it. On top of all this, it also contains collagen, which as previously mentioned is an extremely bad idea as collagen primary causes scar tissue, exactly what should be avoided during SEO use. I am not sure of the price (never been interested in this product). Available from www.apex-pharmaceuticals.com

Liquid Muscle – same as PumpnPose, but at $199.95 per bottle. However, I can’t find too much about it and about who makes it, as it seems as a small outfit and as such I have trouble trusting it 100%, especially when I am supposed to inject their stuff into MY body. They do advertise all over the bodybuilding magazines in the back sections, but that doesn’t mean much. www.liquidmuscle.com

There’s a ton of other brands, but the above are the most well known. The other brands available, I personally would not trust since they come from very small outfits, so you don’t know whether they are sterile, properly manufactured or most likely just mixed together in somebody’s ‘bathtub’.

Site oils can be used for two purposes – to increase the size of a muscle or to shape a muscle.

To increase size, lets use the biceps for example. You need to inject in EVERY head of the muscle, while rotating the shots daily within that head. This is the only way to ensure that the added size keeps to your natural look/shape of the muscle. The quickest way to get a muscle up to maximum size is to do the following regimen: 1ml for 10 days in each head of the muscle. 2ml for 10 days. 3ml for 10 days. If you do both, the biceps and triceps simultaneously, you can add up to 3″ on your arms in those 30 days.
Now, this is VERY IMPORTANT!!!: you HAVE to massage the area that you just injected SEVERELLY! You have to make sure that there’s no lump forming. The muscle should always be soft. You should NEVER have a lump. It is also a good idea, to inject just before going to the gym, so as soon as you get to the gym, you should do a couple light weight, high reps sets for that muscle, to get the blood moving. This again will minimise lump formation. You have to keep in mind, that as soon as lumps form because you did not massage, scar tissue will form as well. You want to avoid scar tissue at all costs. Also, to minimise scar tissue build up, use VERY small needles, like 25g or 26g, inch or 1inch long (depending on the injection site) and inject VERY slowly. If you find that you cannot keep with the lump build up, but you are due for another shot, wait until, by massaging, the lump goes away (it should not be more than a couple of days) and then resume from where you left off.

If you have all the size you wish and just want to shape the muscle, as adding a peak on the biceps, then inject the spot, in the peak of the muscle, with 1ml every day or every second day until you obtain the peak that you desire.

What I recommend to people that are just starting out using these oils is to use 1ml per head of muscle per day, or every second day, for a week or so and see how they react to it. That way they can judge how many ml they can use per muscle head and how often.

Where to inject – BICEPS – inner and outer head. You can feel the `split’ in between the two heads of the biceps when you feel with your other hand. Inject on each side of that. If you want to increase the length/thickness of the bicep, inject more in the inner head (closer to your body). If you want to increase the peak, inject more in the outer head.

TRICEPS – You don’t need to inject in the outer/horseshoe head, unless it is really lacking behind. You inject in the middle and rear heads of the triceps. Generally, at the back of your arm, the upper portion is the rear head and the lower portion is the middle head, as the two heads overlap each other somewhat.

DELTOIDS – just inject straight into whatever head is lacking in size.

CALVES – Natural calves, no matter how big the are, have a `flat’ look to the muscle. So you want to keep that look, you don’t want to have your calves looking round like someone stuck an air hose in there. So, you inject in multiple shots, on the outside edges of the muscle. That will make the calf go outwards, while keeping the flat, natural look.

QUADS – With muscles this large, you need to do multiple daily injections. Where in the biceps you use 1ml per head per day to begin with, on quads you need to start with 1ml per site, 7 sites per quad. That is to avoid the `lumpy’ look and keep the quad uniform. Again, to keep the natural look of the thigh, you should inject in the `peak’ of the outer quad, injecting along the crest. If the teardrop is lacking, then just inject straight into it, rotating sites daily. I personally don’t recommend quad shots, especially teardrop, due to the very high amount of nerves in the area.

PECS – pecs are a very large, ‘flat’ type of muscle. As such, the injections have to cover the entire area of the muscle, to ‘lift’ it at the same time, otherwise a lumpy look will result. I recomend three rows of three shots per pec per day.

I strongly recommend that you get some anatomy charts and study the muscles and the nerves that are in the area that you want to inject.

How do Site Oils work? To begin with, they do not stay in the muscle for 3 to 5 years. They get dissipated within months. However, during this time, they have stretched the fascia of that muscle. The fascia is a great constrictive factor in muscle growth. The more stretched the fascia is the more the muscle will grow and the more it will have that `popping’ look. Site oils stay in there long enough for the fascia to stretch. As they dissipate, the `space’ left by them is replaced with new muscle tissue growth. That is the reason why when x-rays/MRIs where performed on some of the people that have 25″+ arms, there was no oil found in there. The oil dissipated and it was replaced by real muscle.

The principle is the same as the one behind site shots with steroids, but it works at a much a larger degree, because the Site Oils take that much longer to dissipate.
As well, this is the same principle behind fascial stretching. Howver, it is much more efficient with Site Oils. Best example is to imagine a baloon. You can pull on it and stretch it as much as you want, and you will stretch it a bit. But if you fill it with a liquid, you will be able to stretch it to a much larger degree than just pulling on it from the outside. This is the best way to compare the efficiency of fascial stretching versus using Site Oils.

Pain – obviously, any site shot hurts. The pain will minimise the more you inject, until it will not hurt any more. Site Oils hurt, but not as much as site injections with, lets say, Sustanon or Testosterone Propionate. However, as I said, they will hurt less and less the more you use them.

Dangers – Site Oils are safe, if certain precautions are taken, same as when injecting anything else. You always have to aspirate. Always! You DO NOT want the oil to go in a vein. Always massage the area after the shot so scar tissue build up doesn’t occur. And most importantly – USE COMMON SENSE! If you have 16″ arms, don’t think that you will have 23″ in 5 weeks! Because if you try that, you will end up with deformed looking muscles and you will be the laughing stock of the world. On a side note, people like Greg Valentino have implants, not SEO’s in their muscles. It is physiologically impossible to look like these guys do with SEOs. Hopefully that puts that myth to rest.

Site Oils are there to help you break past a plateau. If your genetics indicate that you are 242 with 5% bf, but you only have 18″ arms, then Site Oils will help you bring your arms in proportion. All that I am saying is that Site Oils are there to aid the work that you do in the gym, not replace it!

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This is a general guide for beginning and intermediate bodybuilders that don’t know the principles behind muscle growth yet or are not happy with the results that they are currently getting.

We will go through training, diet and gear. I will tell you the principles behind everything that I recommend for you to do, so you can understand why certain things happen, so in the future you can fix problems yourself. Bodybuilding is a very simple and logical endeavour. Everything that you do has to be logical. Only logical actions will give you results. Every time that you come across a new principle, always ask yourself it it makes logical sense. If it does not, dump it!

TRAINING

Why does a muscle grow? Because it has to adapt. When does it have to adapt? When you expose it to something that it has not done before. When is something that it has not done before? When the muscle is taxed 100%. That’s 100% effort. What’s 100% effort? When you train to 100% PHYSICAL, not mental failure. So, to make the muscle grow, you have to train with 100% effort otherwise, the muscle will not adapt/grow.
Now, using the above logic, for a set to be beneficial to your growth, it needs to be 100% effort. So, a 100% effort set of an exercise, will make you grow. Then, what is the point to do a second set of that exercise? You cannot go more than 100%. The muscle already has been taxed by 100% from the first set, so why should you do a second one? You will just eat into your recovery ability. So, you should only do one set to failure per exercise. Later on, I will describe the training program and how exercises and warm-ups are involved.

A muscle will not grow until it’s recovered. The muscle will not begin to recover until the nervous system is Recovered. It takes roughly 24hours for the nervous system to recover from a workout. Only then will the muscle begin to recover and grow. So, you should never train 2 days in a row. Even if you train different bodyparts, you still use the same nervous system. You train 2 days in a row, your nervous system recovers, but by the time the muscles begin to, you train again, so the body has to concentrate again on recovering the nervous system.

A training frequency of 3 days per week (Mon, Wed, Fri) is more than enough. Numerous pros, including myself, train like this offseason for maximum growth. Even if you use streroids, you still have to train like this. Steroids increase your recovery ability, but they also make you stronger at a quicker rate. The extra strength will give you the ability to train harder/tear more muscle tissue, so you will need the extra recovery that the steroids will give you.

The following is a great training program that I recomend:

Mon – Chest, Shoulders, Triceps
* Incline press – warm-up sets, 1 work set
* Flat flyes – 1 work set
* Millitary press – 1 warm-up, 1 work set
* Lateral flyes – 1 work set
* Rear delt machine – 1 work set
* Tricep pushdowns – 1 warm-up, 1 work set
* Lying tricep extensions – 1 work-set

Wed – Quads, Hams, Calves
* Squats – warm-ups, 1 work set
* Leg press – work set
* Leg extension – work set
* Leg curl – warm-up, work set
* Stiff leg deadlift – work set
* Standing calf raise – work set

Fri – Abs, Back, Bis
* Rope crunches – warm up, work set
* Lat pull down – warm-ups, work set
* Deadlift – warm-up, work set
* Bent-over rows – work set
* Shrugs – work set
* Standing BB curls – warm up, work set
* Concentration curl – work set

You do a lot of warm-ups for your first exercise of the day. You do one warm-up for the first exercise of each bodypart, only to optimise the firing of the neuropathways.
Let’s use chest as an example – if for example your max (work set) in the incline press is 3 plates, then you do 2 warm-ups with the bar, 2 warm-ups with one plate, 1 warm-up with 2 plates and then your work set with 3 plates. The work set is a set where you fail at about 6 reps. Every workout, you have to do more reps or increase the weight in that work set (remember, the muscle has to do something that it has not done before). So if one work out you fail with 6 reps, the following nothing less than 7. When you reach 8 reps, the following workout you should do (increase) a weight where you can do minimum 4 reps. Then increase your reps again every workout until you reach 8 again, and so on. Each rep has a tempo of 2-1-1. That is 2 seconds in the negative, one second in the contraction
and 1 second in the positive. Then, after you fail in the incline press, you move straight to flat flyes. You do not need a warmp now because your chest is more than warm after you failed on presses. And that’s it for chest. The basic routine stays the same. If you want variety, small changes as using DB’s instead of BB or doing flat presse and incline flyes for example, is mor ethan enough variety to keep the muscle ‘confused’.

DIET

VERY simple. Very important that you try to get as close to 500g of protein per day. Easiest way to do that is to have a whey protein shake in water with every meal. Fats and carbs don’t matter. Calories don’t count, macro nutrients (protein, fat, carb) do. If you get to add fat on, just cut out the fats and keep your carbs bellow 300g/day. That’s all it is! Very simple, but hard to stick to, so not many people get results. On gear, the more protein you eat, the more you grow. Is as simple as that. Gear maximises protein synthesis.

GEAR

You need a testosterone base. 750mg/week is plenty. You need an anabolic – deca or Eq at 400mg/week is plenty. You need for optimum growth, a good oral like d-bol at 30mg/d or A-50 50mg/d. You use the test and the anabolic non stop. The oral is 4 weeks on 4 weeks off. Every 6th week (the half way point between the off oral period – so 2 weeks after you finish the oral) you have a blood test. If the blood test is OK, then you can begin your next 4 weeks on oral. There is no reason for you to come off. The only 2 reasons are health or your receptors are saturated. If the regular blood test is OK, your health is OK. If you are still making progress, your receptors are OK. Coming off, will just sabotage your gains. That’s why I do not believe in set time frames for cycles. Listen to your body. When you use the oral, you need to use all the liver aids available – Synthergine, Milk Thistle, L-methionine, Liv-52, etc. Of course you cannot drink or do rec drugs during that time. Using these precautions, your blood tests will be OK.
You also need to use an anti estrogen like Nolvadex at 10mg/d throughout the whole time. Also, you have a choice between HCG every 4 weeks at 5000IU or Clomid at 50mg EOD. These will make sure that your balls will stay at a decent size and they will not forget how to function. The blood tests that you need are: full blood count, liver and kidney function tests, FSH, LH, TSH, cholesterol. If the Total protein test in the liver tests is high, that is because of your diet. You need to keep an eye on the Billirubin and Urea test results. Your FSH and LH will be suppressed – that’s normal because of the gear. If the TSH is low, add 20mcg/d T3. If the kidney function is off, then drink more. Protein stresses the kidneys, so you need more fluids. When you eventually come off the gear, you make sure that you are off the orals. Then cut out the anabolic over 2 weeks. Then the testosterone over 3 weeks. One week after that, you need to add primo tabs or anavar (oxandrin) for 3 weeks. That will ensure that you will keep your gains.
Ideally do a gainkeeper’s formula that is outlined in another article.

These are the basic principles behind muscle growth. You do the above you will GROW, no matter what.

To Discuss This Article Further, Please Click The Link Below:
http://www.professionalmuscle.com/forums/showthread.php?t=1158 ]]> http://www.synthetek.com/growth-principles-for-beginners-by-big-a/feed/ 0 http://www.synthetek.com/dieting-and-getting-ready-for-competition-by-big-a/ http://www.synthetek.com/dieting-and-getting-ready-for-competition-by-big-a/#comments Thu, 04 Jun 2009 06:29:51 +0000 http://www.synthetek.com/wordpress/?p=111

Competition dieting is rather an individual matter as far as success goes. Generally, if one is in a calorie deficit, while maintaing a very high protein content and taking anabolics, that person will lose minimal muscle if any at all while losing a great deal of bodyfat. Add to that combo fat burning aids, and one can achieve stage shape very quickly.

Below is a standard formula that I used succesfully on many people. It is designed to make one in competition shape in extreme time. The biggest change so far has been one person that went from 21% to 4% bodyfat in the 9 weeks of the preparation.

DIET – Weeks 9 & 8

06.00 am training

08.00 12 egg whites, 1 apple, protein shake

10.00 100g rice, 1 apple, protein shake

12.00 red meat, salad (tomato, lettuce, cucumber), protein shake with 10g flax seed oil

14.00 100g bread, 1 apple, protein shake

16.00 tuna or chicken or fish, protein shake

18.00 100g maltodextrin, 1 apple

18.30 pm training

20.30 chicken or turkey or fish, salad, protein shake

21.30 run (20 – 30) minutes

This diet is to be followed Monday to Saturday. On Sunday, as many carbs as desired are allowed. Training is performed Mon to Sat with Sun off. Running is performed every night.

This diet is the diet for the weeks 9 and 8, competition being at end of week 1. The times on the diet are as an example and they should be modified to suit ones needs. However, DO NOT miss meals and DO NOT swap them
around!!! The aim here is to only have the amount of carbs outlined on the diet. Fat is absolutelly minimal. Protein is at maximum. On this diet, you should never feel hungry. If you do, eat more protein.

After 2 weeks of this diet, you will drop the maltodextrin carb meal. Two weeks later, you will drop the bread carb meal. Two weeks after that, you will drop the rice meal. That will leave you 2 weeks on virtually no carbs. Don’t worry, by then, the body is used to using fat for energy, so you won’t have any problems. The hardest days will be the first week of your diet, until you will get used to using fat for energy.

When you drop a carb meal, replace it with a protein meal.

On the weekends, you can have as many carbs as you wish, but they have to be CLEAN carbs, so no McDonalds!

The last week, will be a full on carb week while you adjust your water levels. I will detail that in another article.

TRAINING

MONDAY

AM TRAINING Biceps, Triceps

* Bicep curl B.B. – 2 x superset 10/15
* Preacher curl (mach.) – 2 x superset 10/15

* Rope pushdowns – 2 x superset 10/15
* Dips b/w benches – 2 x superset 10/15
PM TRAINING Chest

* Incline press – 10, 8, 6, 12 (2min rest)
* Flat flyes – 8, 6, 6 (1min rest)
* Cable crossovers – 10, 10, 10, 10, 10 (40sec rest)
TUESDAY

AM TRAINING Back

* Lat pulldowns – 2 x superset 8/12
* Bent-over rows – 2 x superset 8/12
* Shrugs – 2 x superset 8/12
PM TRAINING Shoulders

* Millitary press – 10, 8, 6, 12 (2min rest)
* D.B. Press – 8, 6, 6 (1min rest)
* Rear delt machine – 10, 10, 10, 10, 10 (40sec rest)
WEDNESDAY

AM TRAINING Hams, Calves

* Lying leg curl – 2 supersets – 10/15
* Stiff legged deadlift – 2 supersets – 10/15

* Standing calf raise – 2 supersets – 8/10
PM TRAINING Quads

* Squats – 10, 8, 6, 12 (2min rest)
* Leg press – 8, 6, 6 (1min rest)
* Leg extension – 10, 10, 10, 10, 10 (40sec rest)
THURSDAY

AM TRAINING Chest

* Incline press – 2 supersets – 8/10
* Flat flyes – 2 supersets – 8/10
PM TRAINING Biceps, Triceps

* D.B. curl – 10, 8, 6, 12 (2min rest)
* Concentration curl – 8, 6, 6 (1min rest)
* Preacher curl (mach.) – 10, 10, 10, 10, 10 (40sec rest)

* Rope pushdown – 10, 8, 6, 12 (2min rest)
* Lying extension – 8 ,6 ,6 (1min rest)
* Dips b/w benches – 10, 10, 10, 10, 10 (40sec rest)
FRIDAY

AM TRAINING Shoulders

* Front raises – 2 supersets – 8/10
* Lateral raises – 2 supersets – 8/10
* Rear raises – 2 supersets – 8/10

PM TRAINING Back
* Lat pull downs – 10, 8, 6, 10 (2 min rest)
* Bent-over rows – 8, 6, 6 (1 min rest)
* Shrugs – 10, 10, 10, 10, 10 (40sec rest)
SATURDAY

AM TRAINING Quads

* Squats – 2 x superset 10/12
* Leg press – 2 x superset 10/15
* Leg extension – 2 x superset 10/15
PM TRAINING Hamstrings, Calves

* Lying leg curl – 10, 8, 6, 12 (2min rest)
* Stiff leg deadlift – 8, 6, 6 (1min rest)
* Seated leg curl – 10, 10, 10, 10, 10 (40sec rest)

*Standing calf raises – 10, 8, 6, 12 (2min rest)
*Leg press calf raises – 8, 6, 6 (1min rest)

Abs are performed every workout. All days begin at 06.00 am.
This is the training set-up:

Bis, Tris Back Hams, Calves Chest Shoulders Quads Rest
Mon Tue Wed Thu Fri Sat Sun

Chest Shoulders Quads Bis, Tris Back Hams, Calves Rest

This is a very intense program. It’s designed to give
maximum fat loss in minimal time with no muscle loss.
It is VERY time consuming, but it’s guaranteed to work
and it’s only for 9 weeks.
GEAR

Use normal bulking gear until 4 weeks out (test, a-50, d-bol, deca, etc). 4 weeks out switch the test to test propionate or suspension. Drop the Deca/EQ, etc. Add primobolan, tren, winny, etc. One week out, only use tren, masteron, suspension, primo tabs, winny.

Use GH throughout – as much as you can afford. No insulin.

Use Arimidex or Nolvadex every day as desired. To keep your testes at a normal size, either use HCG every 4th
week (2,000IU on Mon, Wed, Fri) or 50mg EOD of Clomid throughout the whole thing. Don’t use these for the last 4 weeks before the show though.

Cutting compounds: Use a good ECA product like SyntheBURN twice a day, every day. Use Clenbuterol at 80mcg/day for the first week. Increase it to 160mcg/d for the second week. The third week you add 25mcg/d T3. You add another 25mcg/d every week following that, until you reach 150mcg/d. You stay on that until the end of the diet. You stay on Clenbuterol thoughout as well. Yes, you will be racing! But you will not loose any muscle, so do
not worry about that (as long as you take your protein in).

Last week do your diuretics program. That will be outlined in another article. One hour before stage time use Synthelator. It’s use is outlined on the board. Use the Search engine.

This program will get you in competition shape pronto while keeping all your size on. If you appear to be losing muscle, eat more protein!

To Discuss This Article Further, Please Click The Link Below:
http://www.professionalmuscle.com/forums/showthread.php?t=1157 ]]> http://www.synthetek.com/dieting-and-getting-ready-for-competition-by-big-a/feed/ 0 http://www.synthetek.com/great-information-on-protein-by-massive-g/ http://www.synthetek.com/great-information-on-protein-by-massive-g/#comments Wed, 03 Jun 2009 06:39:16 +0000 http://www.synthetek.com/wordpress/?p=115 First off everyone should learn how there body reacts to protein and how their metabolism is. Just like training. To me nutrition is 70% of the battle and responsible for most of my gains no matter what AAs or how I trained my gains were/ are concurrent with my nutrition program. I eat a high protein diet that’s no secret. My body hates carbs. I eat very few simple sugars and mostly complex carbs and those are cut by 7 PM. I wrote this post a while ago in reference to eating the protein first in a meal. I beleive in eating for function. That is protein first, carbs second, veggies last. I don’t mix fats and carbs the only time I mix simple sugars and proteins are in my pre and post work out shakes. A lot depends on the absorbability of the protein itself which is influenced by it’s type. A lot of old timer will remember this thing called the P.E.R. or the Protein Effeciency Ratio from the early 1990’s. This was before Whey Protein and it was used to sell egg and milk proteins commercially. I think Nature’s Best abused that line the most as I was seeing “P.E.R. P.E.R. P.E.R.” dancing through my head at night while I slept.
Things like Eggs and fish are more complete protein and absorbed better than ground beef and pork, chicken and turkey are better absorbed than soy and milk proteins etc.

I routinely eat 600 grams of protein a day without blinking over 3-4 solid meals and 3-5 shakes that includes daily pre and post and night time shakes. Sometimes I will drink pastuerized egg whites as a meal replacement which is 50 grams per pop. I am lucky my digestion is in very good shape and when ever I post a diet people always reply “You must be on the toilet all day” nope not to discuss this “shit” but I stay regular whether on 600 800 or 400 grams of protein a day.

Here is some of the post I wrote on eating protein first and eating for function: There was a recent thread on Mayhem in which someone questioned DANTE’s advice to eat the protein first. I thought I’d share it here and added some more clarification on my part why we do this. Dante could probably write 2 books on this stuff so what I write most already know or maybe not. Every few years I have posted it and always get a few people that benefit from it. DC’ers already eat proteins first but I thought I’d share why since I have eaten for function since day 1.

DC::Think for a second–If you fill your hunger with protein first what are you most likely not going to eat a huge amount of? It takes roughly 24.6-26 calories burned to digest every 100 calories of protein yet it only takes roughly 3.8 to 4.2 calories burned to digest every 100 calories of fats/carbs so are you figureing out yet why my trainees are always hot like a furnace and stay reasonably lean eating gross amounts of food?

If I can add something here to further back Dante’s theories:
Eating protein first in a meal increases the effeciency of digestion and a greater overall amount of protein as an end result in from a meal. In short a greater amount of aminos make it to the blood stream. Everytime I have written about this in the past few years people always are like “WOW I learned something new today”.

I call it eating for function…the function of the digestive system.
I eat proteins first for 2 reasons-that digestive system is physiologically(enzymatically) geared that way and it improves the effeciency of digestion and a greater overall availability of proteins/aminos from food for the body to use.

Carbohydrates are digested 30% in the mouth with the salivary enzyme amylase and with of course chewing aiding the cause. CARBS aren’t digested in the stomach=they just sit there and slowly pass into the small intestines where the pancreatic enzymes do 70% more and complete the process. Fats are the same way if eaten first or mixed with carbs will sit there and clog up digestion.

Proteins are primarily digested in the stomach. Therefore, eating proteins after these foods will result in a reduced amount of protein digestion-leaving some incompletely digested and unabsorbable and therefore lost. This in turn causes the undigested protein to be pulled into the small intestine reducing the protein effeciency of your meal and contributing to the mass of your colon.

You want something worse? We are set up by traditional eating to fail. Go out to a steak house. First thing you get is your salad-THAT is the last thing you want to eat in a meal after the steak and then the potato. Cellulose is undigestable by the human body and will really clog up the process reducing the effeciency of digestion and your meal itself.

As mentioned previously proteins speed up the metabolic rate more than carbs and fat. Concerning basal metabolism proteins speed it up 30%, Carbs and fats 10%. The mere process of digestion and absorbtion of protein races the metabolism and will increase anabolism in an advanced athlete.

Now granted you can eat a huge meal like a McDonald’s Combo meal mix it all up and it will get digested but it will interfere with feedings and the effeciency of the meal will be less and eventually lead to a lot of adipose tissue gain.

There are reasons we eat Protein and Fat together and protein and carbs. Insulin. Eating fat and carbs are a death warrant to bb’ers when consumed together and lays adipose tissue down as easily as Home Depot lays down cheap carpet.

I could write more especially on the types of proteins and their absorbtion-things like incomplete proteins etc.

Anyhoo..just my 2 cents. We are all here to learn from each other but Dante’s methods are backed by science and 3-4 years of online “University” studies with 100’s reaping the benefits-so it is good advice and gospel for most ADVANCED lifters.

PEACE.
This was a good post too in the thread:
Protein will serve you a dual role in body modification in that it is as important for body fat reduction as it is for muscular gains. In regards to body fat reduction, protein has a specific dynamic action on the metabolism which means that when you ingest protein, your metabolic rate is elevated higher and remains elevated longer than when you ingest either fats or carbohydrates. A high carb meal will only elevate your metabolism from 4 to 30 percent above normal. This small elevation will last only 2 to 5 hours. A high protein meal however will elevate your metabolism by up to 70 percent above normal and this effect can last as long as 10 to 12 hours.”

The entire thread is on mayhem and I thought I’d bring at least some good points out of it and add it here for others benefits.

http://www.chadnicholls.net/forums/…ead.php?t=19663

Very easy to squeeze a lot of protein in Raj if that is your goal. You can eat 4 meals a day and squeeze in protein shakes in between meals as well as your post WO and night time shake will be contributing heavily to your overall daily count.

I don’t use commerical proteins I use eithe TP’s Whey ion X @90 grams per serving or eggwhites in liquid form @ 50-60 grams per serving, and or liquid beef aminos in between or with a meal to contribute to the overall. All of the above don’t clog up my appetite or bloat me so it is easy to get 9-10 feedings a day for a 24 hr amnio pool to pull from.
I really like the night time anticatabolic shakes and have been taking them for over 5 years now.

I used to wake up flat in the morning and find sleep very catabolic. I have always used a micellar casein/Calcium caseinate/whey Ion X/Glutamine blend which I buy in bulk from true protein and previously protein customizer and or the factory.

I would like to state too I am always learning always searching and always experimenting with foods. There are a lot of things I wanna try and Phil and Dante and some other guys out there that are tops in the nutrition department see questions from em often and I may switch diets later in life as I tone things down. Currently, high protein is what works for my goals in buliding and maintaining muscle.

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My thoughts on those thinking of doing a show
As I am sitting here at my shop, 1 week out, I felt like typing up something to kind of give some insight to those that are thinking of doing a show. You see many people thinking of doing a show, but 9 times out of 10 they never get on stage. Hopefully I can shed some light on what goes into the process of pre-contest dieting and all the odds and ends that follow. Many may know this stuff allready. Those that don’t, or that wondered what to do, this may be a starting point.

TIME- Its all about time to a certain degree. I really feel that this is one of the most important factors in your prep. You need to pick a date and stick to it. Allow yourself enough time to get ready for your show. If this is your first show you are gonna need extra time. I suggest about 16 weeks to diet for your first show. Some may not agree but it is better to be early than behind and if you have never dieted before, your body may take a little longer to get into the swing of things and take to a diet. Better safe than sorry.
STICK TO YOUR GAME PLAN- There are several ways to diet and everyone is so different that what works for someone else may not work for you. I kinda feel that the best way to diet is to plan it out and stick to it to the very end. What I mean by this is when you start listening to 10 other people, you run the risk of second guessing what you have done up to that point which can lead to making mistakes. The nice thing about sticking to one diet is that if you dont end up looking the way you want, you now know that this way may not be the best for you and you are slowly taking some of the guess work out of your next contest prep. If you try a bunch of different stuff at the end, you dont really know what worked and what didnt so its better to just stay the course of the original plan.
HAVE EVERYTHING AHEAD OF TIME- Things like your pro tan, suits, and other odds and ends are all things that may not seem important enough to be thinking of at 8 weeks out, but it sucks to be running around town looking for a bottle of tan when you could have planned ahead of time. If its a local show, most of the shops will be selling a ton of that stuff at the last minute, so there is a good chance that the longer you wait to buy that stuff, the better chance they have of being out of it. You are not gonna buy your posing suits at 8 weeks out, but its a good idea to know where to go or if you have to order them to see how long it will take to get them if you have to send them back if something is wrong.
Food is another thing that you dont want to be out of either. I like to make lists of things I need and I try to keep track of how much I have left of something so I dont run out at 10pm the night before. Try and keep extra bags of chicken, fish, rice, ect on hand so you are prepared to cook all your meals without having to run all over the place in a panic.
MONEY- Dieting is not cheap. It does not have to break your bank, but you have to know ahead of time that the whole process is going to cost extra money above and beyond what you might normaly spend. This all goes back to the time thing I mentioned earlier. If you know that in 6 months you are going to have to start your diet, start to save a little so that you have extra cash to make sure everything runs smoothly. I try to shop at Sams, Costco, ect to save money and I really try to watch my budget so I dont get into a bind where I cant afford something I really need.
YOU ONLY CAN DEPEND ON YOURSELF- Really that is the only person that is going to be there for you 100% of the time. What I mean by this is that when you start expecting other people to help you do things for you, you may get let down and put on the back burner. Its nice to have someone help you with your prep, but just be prepared to do everything yourself. Plus I think it really helps your learn about yourself and helps you stay more focused.
DONT BE AFRAID TO LOSE WEIGHT- I know this sounds strange, but one of the biggest mistakes is that most will sacrifice conditioning for size. You see that a ton at local shows. Be strict with your diet and have faith that you are doing everything you can to come in the best condition you can. Its better to be a little smaller and in great condition, than bigger and soft.
DON’T FORGET TO PRACTICE- Practice makes perfect and posing is one of the most important aspects of how you present what you have worked so hard to show. Practice your 1/4 turns and manditories every night and get used to not doing them in front of a mirror so it feels natural. The more you pose, the better your stage presence will be.
HAVE FUN- Its wierd to see guys on stage all serious looking. Smile, smile, smile…..make eye contact with the judges and have a good time. Keep in mind that everyone in that audience is there to see bodybuilding/figure/fitness and are fans of the sport. When somebody is all serious looking and not smiling, it makes them look uncomfortable and the judges notice that. The more relaxed and poised you are on stage, the better youll look in my opinion. With that in mind, don’t get hung up on placing if its your first show or whatever. Seriously you are one of the few that actually make it on stage and have the guts to put yourself in position to be judged on the merits of your physique. That in itself is an accomplishment.
So there is my take so to speak. Many may know most of it, but I just needed to pass some time and I thought maybe this might help a couple out there that thinking of gettting on stage.

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In the field of muscle science, There has been much more extensive research performed on how to develop strength and none of it involves 1 set to failure or 3 sets to failure. Power lifting and Olympic weightlifters are very critical and precise about their training programs. Many countries view their weightlifters as the pride of their nation in the Olympics. Soviet weightlifters have coaches who are not only experts in human kinetics and the human body but they have been studying and coaching weight lifting for years and have coached tons of athletes to perform fetes such as clean and pressing 500 lbs. over head at a bodyweight of 165 lbs.

Most of the best training information comes for Eastern Block countries and the Soviet Union (not flex magazine and not Mike Mentzer articles). When it comes to strength, speed, and hypertrophy training the Western World is very far behind. This is evident as America or all of North America for the matter has always done very very poorly in international Olympic lifting and power lifting for the most part, hell–sports in general. Please note that we are one of the largest countries and have the most people/athletes to select from.

L. Simmons from West-Side Barbell began to research the methods of these countries; Particularly the methods of the Old Soviet Union. Upon applying these soviet methods to conventional power lifting, his lifts began to explode and his injuries disappeared. He continually refined his system and now he currently has many World Record Holders lifting under his guidance. Bigbyrd, who is a member of this board follows L.Simmons methods and is a world record holder in the squat.

These countries/athletes DID NOT develop these Super human fetes of strenght with Low Volume (at least in terms of what H.I.T programs consider low volume). Neither do they usually train to maxium failure with sub maximal weights in attempt to build maximal strength. A lot of people like to say how West Side builds up to a “max set” and then they compare this to the HIT Method. They are actually building up to 1 RM. more importantly a MAX EFFORT usually over 8 to 10 sets, it is actually much different. This is not the same at all and the only reason the volume is “somewhat low” is because they are working with training percentages above 90%. They work all they way up 100%. More basic power lifters programs and Olympic programs, which use lower percentages, use much more volume. Keep in mind that many of these Olympic athletes are drug tested. Whether or not they use drugs in some point of their training, they still have to pass the test for the Olympic games. Can this be said for most successful HIT strenght athletes?

This article by L.Simmons explains how H.I.T is not a good method for strength. He points out that college athletes who use these methods to strength train always test very poorly at the columbine when trying to go to the NFL. It is not a sports specific training program either. In IRON MANs thread he recommended the program for athletes as well as weightlifters and bodybuilders.

http://www.westside-barbell.com/Arti…/01PDF/HIT.pdf

The link below is a very basic training template of West side barbell, it explains the basic concepts of the program, There is MUCH MUCH more involved behind it than this. I just wanted to post this to show that this method does not resemeble HIT as many people compare HIT to this.

http://www.t-nation.com/findArticle….le=body_133per

I’d like to point out one part that Dave Tate talks about in the above article called the Repetition Method. They use this method to build hypertrophy for supporting muscle groups such as lats, triceps, biceps etc. or for a powerlifting wishing to gain weight. again based off of soviet research. I have interviews by L. Simmons and he goes into this more thoroughly about training muscles for hypertrophy with more exact protocols.

The Repetition Method
The repetition method, otherwise known as the bodybuilding method, is the best method for the development of muscle hypertrophy (growth). This is the method in which all supplemental and accessory exercises are trained. This method is defined as “lifting a non-maximal load to failure.” It’s during the fatigued state when the muscles develop maximal force. According to this method, it’s only during the final lifts that, because of fatigue, the maximal number of motor units are recruited. This system of training has a great influence on the development of muscle mass which is why it’s become so popular among the bodybuilding population. The fact that the final lifts are performed in a fatigued state makes this method less effective compared to the others when it comes to maximal strength development. This is one of the reasons why powerlifters are much stronger than bodybuilders. Another disadvantage of this method is that each set is carried to failure. This makes it very difficult to increase your volume and work capacity over time because of the amount of restoration needed. Training to failure is very hard on your ability to recover and in my opinion should only be used sparingly. When you extend a set to failure many times, the last few reps are performed with bad technique and this, of course, can lead to injuries. Westside has modified this principle to what I refer to as the modified repetition method. With the modified version all sets should be stopped with the breakdown of technique and there should always be a rep or two left in you. Remember this principle is applied to all supplemental and accessory movements. These movements are designed to be exactly what they are: supplemental and accessory. The main goals of these movements are to complement the overall training program, not take away. By training to failure on every set you’d be taking away from the general purpose of the movements, which is to increase work capacity. The parameters of this method are varied and depend upon the individual. Some athletes develop muscle mass with high reps and other with low reps. It would be crazy to assume one specific rep range works for everybody. What we’ve found to be best with supplemental and accessory work are sets in the range of 5 to 8 with repetitions between 6 and 15. This is a rather large range, but as I mentioned before, everybody is different. If you’ve been training for some time, I bet you have a better idea of what works for you than I could ever prescribe. The load or weight to be used should fall in the 60 to 80% range and you should always leave a rep or two at the end of each set. Try to switch the exercise after every one to five workouts in which it’s used. If you decide not to switch the exercise then switch the way it’s trained. Try to add an extra set for a few weeks. Try to work it up for four weeks then deload it for four weeks. The point is to change it up as much as possible.

Modified Repetition Method Parameters
Load (Intensity) 60 ? 80%
Number of Exercises All Supplemental and accessory
Sets / Repetitions 5-8 / 6 – 15
Rest Interval 1 to 3 minutes
Frequency / Week All workouts
Weeks per Exercise 1-5
*NOTE—there are many other methods that have been show to be good for hypertrophy. All of which use some form of volume. Also note that they recommend training just shy of failure or if u do train to failure do not over indulge

There are articles I would like to post on here about hypertrophy, however they are only in PDF format and they are not on the web. Some I have on paper. However, all research that is held with the highest regard illustrates that hypertrophy is accomplished best with larger amounts of Volume (in terms of sets/reps); Focussing on targeting the tissue instead of trying to lift the heaviest load possible. It could be as simple as performing 4 sets of 12.

Regardless of anyone’s thoughts on HIT of it being the best system or not. It should be noted that absolutely ZERO of the elite power lifting teams or Olympic teams Train in this fashion whether they are seeking maximal strength or trying to build muscle mass.

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This article makes it look like a wonder drug and I will be doing a controlled study with myself to accurately assess it’s effectiveness in accomplishing this in the next few months and will define the dosing and protocol use when done-including some accurate notes from the log book.

I am planning on doing back to back comparisons with the only variable being the added Bromelain itself to accurately assess it’s effect. Everything will be planned to be kept the same in each study. Training style, DIET (food), supplementation, and possibly no AAS or if so , Enhanced HRT doses only. I’ll do my best to keep stress and other things to a minimum.

Oh yea plus blood work before and after each study to see the effects on tha blood. (Thank God for www.directlabs.com)

Read up and comment please.

“Bromelain: A Literature Review and Discussion of its Therapeutic Applications

Gregory S. Kelly, N.D.

Abstract

First introduced as a therapeutic compound in 1957, bromelain’s actions include: (1) inhibition of platelet aggregation; (2) fibrinolytic activity; (3) anti-inflammatory action; (4) anti-tumor action; (5) modulation of cytokines and immunity; (6) skin debridement properties; (7) enhanced absorption of other drugs; (8) mucolytic properties; (9) digestive assistance; (10) enhanced wound healing; and (11) cardiovascular and circulatory improvement. Bromelain is well absorbed orally and available evidence indicates that it’s therapeutic effects are enhanced with higher doses. Although all of its mechanisms of action are still not completely resolved, it has been demonstrated to be a safe and effective supplement. (Alt Med Rev 1996;1(4):243-257)

Description

Pineapple has been used as a medicinal plant in several native cultures and bromelain has been known chemically since 1876. In 1957, bromelain was introduced as a therapeutic compound when Heinicke found it in high concentrations in pineapple stems.

Bromelain is a general name for a family of sulfhydryl proteolytic enzymes obtained from Ananas comosus, the pineapple plant. It is usually distinguished as either fruit bromelain or stem bromelain depending on its source, with all commercially available bromelain being derived from the stem.1 The term bromelain will be used to refer to stem bromelain in the remainder of this article.

Bromelain’s primary component is a sulfhydryl proteolytic fraction. Bromelain also contains a peroxidase, acid phosphatase, several protease inhibitors, and organically bound calcium. When the proteolytic fraction of bromelain is purified and extracted, the result is a potent proteolytic enzyme in vitro; however, this component has been shown to be physiologically inactive in vivo for many of the conditions where bromelain has a beneficial effect.2 It appears that a great deal of the physiological activity of bromelain is not accounted for in its proteolytic fraction and it is likely that the beneficial effects of bromelain are due to multiple factors, not to one single factor that can be isolated.

To date, eight basic proteolytically active components have been detected in the stem. The two main components have been labeled F4 and F5. The proteinase considered to be the most active fraction has been designated as F9, which comprises about 2% of the total proteins. It is estimated that 50% of the proteins in F4 and F5 are glycosylated, whereas F9 was found to be unglycosylated. The optimal pH for the F4 and F5 fractions is between 4.0 and 4.5 and for F9 close to a neutral pH.3 The entire extract of bromelain has been shown to exhibit its activity over a pH range of 4.5 to 9.8.4

Since bromelain is derived from a natural source, different sources can exhibit variability in their physiological activity, even when their proteolytic activity is the same. Bromelain is not heat stable so it’s physiological activity can be further reduced by improper processing or storage conditions.

Absorption and Availability

Bromelain is absorbed intact through the gastrointestinal tract of animals, with up to 40% of the high molecular weight substances detected in the blood after oral administration. The highest concentration of bromelain is found in the blood 1 hour after administration; however, its proteolytic activity is rapidly deactivated,5 probably by the normal plasma protease controls and serum alpha2-macroglobulin.

A variety of designations have been used to indicate the activity of bromelain; with published research varying in the designation utilized. Rorer units (R.U.), gelatin dissolving units (G.D.U.), and milk clotting units (M.C.U.) are the most commonly used measures of activity. One gram of bromelain standardized to 2000 M.C.U. would be approximately equal to 1 gram with 1200 G.D.U. of activity or 8 grams with 100,000 R.U. of activity.

Platelet Aggregation, Fibrinolysis and Anti-Inflammatory Activity

The first conclusive evidence that bromelain prevents aggregation of blood platelets was reported in 1972. Bromelain was administered orally to 20 volunteers with a history of heart attack or stroke, or with high platelet aggregation values. Bromelain decreased aggregation of blood platelets in 17 of the subjects and normalized values in 8 of the 9 subjects who previously had high aggregation values.6 In vitro studies have demonstrated that bromelain inhibits platelet aggregation stimulated by ADP or epinephrine, as well as by prostaglandin precursors, in a dose-dependent manner.7

Bromelain is an effective fibrinolytic agent in vitro and in vivo; however, its effect is more evident in purified fibrinogen solutions than in plasma. This is probably due to the antiproteases present in plasma. A dose-dependent reduction of serum fibrinogen level is seen in rats following administration of bromelain, and at the highest concentrations of bromelain, both prothrombin time (PT) and activated partial thromboplastin time (APTT) are markedly prolonged.8 Bromelain’s fibrinolytic activity has been attributed to the enhanced conversion of plasminogen to plasmin, which limits the spread of the coagulation process by degrading fibrin.9

Bromelain seems to have both direct as well as indirect actions involving other enzyme systems in exerting its anti-inflammatory effect. Both etodolac and bromelain inhibit the inflammatory pain in rats in a dose-dependent manner.10 Bromelain was the most potent of nine anti-inflammatory substances tested on experimentally-induced edemas in rats;11 while prednisone and bromelain have been shown to be comparable in their ability to reduce inflammation in rats.12 Treatment with bromelain and emorfazone has been shown to decrease significantly the heat-evoked immunoreactive substance P release and subsequent edema in a rat model.13

Mechanism of Action

Surface contact, by collagen or platelets, activates the kinin system and the clotting cascade by stimulating the conversion of Hageman factor to an active protease (factor XIIa). Factor XIIa then activates the kinin system by converting plasma prekallikrein into kallikrein, and continues the intrinsic path of the clotting cascade by converting factor XI to its active form. Kallikrein, in an autocatalytic loop, accelerates the activation of Hageman factor, which continues to potently activate both the kinin system and the clotting cascade. In addition, Kallikrein cleaves (HMWK) to produce bradykinin, a potent stimulator of both increased vascular permeability and pain. The activation of the clotting cascade will culminate in the conversion of fibrinogen to fibrin (see Figure 1). Fibrin then forms a protective matrix around the injured area. This matrix inhibits tissue drainage, promotes edema and blocks circulation of blood flow.

In order to determine the effects of bromelain on the plasma kallikrein system, bradykinin levels and plasma exudation at the inflammatory site were examined in rats. Bromelain (5 and 7.5 mg/kg) caused a dose-dependent decrease of bradykinin levels at the inflammatory site and a parallel decrease of the prekallikrein levels in sera. Plasma exudation was also reduced dose dependently. Bradykinin-degrading activity in sera was elevated after treatment with bromelain, although it was unchanged in the pouch fluid.14 The levels of high molecular weight (HMW) kininogen and pre-kallikrein in rat plasma were markedly reduced after single injection of bromelain (10 mg/kg, i.v.) and gradually recovered over a 72 hour period. The level of low molecular weight (LMW) kininogen was not changed during this period.15

Bromelain-treated rats also show a reduction in Factor X and prothrombin, both of which are needed for the activation of fibrinogen to fibrin through the common pathway of the intrinsic and extrinsic cascade.16 This indicates that bromelain’s action is in part a result of inhibiting the generation of bradykinin at the inflammatory site via depletion of the plasma kallikrein system, as well as limiting the formation of fibrin by reduction of clotting cascade intermediates. These actions result in significant reduction in pain and edema, as well as enhanced circulation to the injured site.

After the formation of a clot, vessel repair begins with the conversion of plasminogen to plasmin, which then acts to degrade fibrin into smaller components which can be removed by monocytes and macrophages. In rats, bromelain has been shown to stimulate the conversion of plasminogen to plasmin, resulting in increased fibrinolysis. This minimizes venous stasis, facilitates drainage, increases permeability and restores the tissue’s biological continuity.16

The therapeutic effect of bromelain may also be due to its ability to selectively modulate the biosynthesis of thromboxanes and prostacyclins; two groups of prostaglandins with opposite actions which ultimately influence activation of cyclic-3,5-adenosine (cAMP), an important cell-growth modulating compound.

The binding of epinephrine, collagen, or thrombin to platelets activates the enzymes phospholipase C and phospholipase A2 which release arachidonic acid from membrane phospholipids (phosphatidylcholine and phosphatidylinositol). Table 1 lists the inflammatory actions of arachidonic acid metabolites.

Plasminogen, which is activated to plasmin by the oral administration of bromelain, has been shown to inhibit the release of arachidonic acid from cell membranes, resulting in decreased platelet aggregation and modulation of the series 2 prostaglandins.17 It is also hypothesized that bromelain therapy leads to a relative increase of the endogenous prostaglandins, PGI2 and PGE2 over thromboxane A2.18

Non-steroidal anti-inflammatory drugs inhibit cyclooxygenase, which is required for the synthesis of series 2 prostaglandins, resulting in a decrease in both pro and anti-inflammatory prostaglandins. Rather than blocking the arachidonic acid cascade at the enzyme cyclooxygenase, like NSAIDs, bromelain may selectively decrease thromboxane generation and change the ratio of thromboxane/prostacyclin (PGI2) in favor of prostacyclin (see Figure 2). Bromelain, similar to NSAIDs, has been shown to inhibit PGE2, however, its action is significantly weaker.16 Table 2 lists bromelain’s impact on selected mediators of inflammation.

Antitumor

The first documented use of oral bromelain on cancer patients was in 1972. Twelve patients with ovarian and breast tumors were given 600 mg of bromelain daily for from 6 months to several years, with reported resolution of some of the cancerous masses and a decrease in metastasis.19 Bromelain in doses of over 1000 mg daily has been combined with chemotherapeutic agents such as 5-FU and vincristine, and has been reported to result in tumor regression.19,20

Bromelain has also decreased lung metastasis of Lewis lung cancer cells implanted in mice in a dose-dependent manner. This antimetastatic potential was demonstrated by both the active and inactive bromelain, with or without proteolytic and anticoagulant properties.21,22

Cytokine Induction

The successful initiation of an immune response depends on T cells and macrophages, along with the polypeptide factors they produce, called cytokines, which play a key role in communication during normal immunological response as well as infectious, inflammatory, and neoplastic disease states. Table 3 lists cytokines and their activities.

Bromelain, papain, and amylase have all been demonstrated to induce cytokine production in human peripheral blood mononuclear cells. Treatment leads to the production of tumor necrosis factor-alpha (TNF-alpha), interleukin-1-beta (IL-1 beta), and interleukin-6 (IL-6) in a time and dose-dependent manner. Interferon-alpha (IFN-alpha) and interferon-gamma (IFN-gamma), which had no effect alone, synergistically increased TNF-alpha production when applied together with the enzymes.23,24 The tryptic but not the autolytic fractions of papain and bromelain have a higher (10- to 40-fold) inducing capacity for TNF production than the untreated enzyme.25 Trypsin alone had only a small inducing effect.

The ability to induce cytokine production may explain the antitumor effects observed after oral administration of polyenzyme preparations.

Immunity

Bromelain has been shown to remove T-cell CD44 molecules from lymphocytes and to affect T-cell activation. The highly purified bromelain protease F9 was tested on the adhesion of peripheral blood lymphocytes (PBL) to human umbilical vein endothelial cells (HUVEC). Both bromelain and protease F9 reduced the expression of CD44, but F9 was about 10 times more active than bromelain; having about 97% inhibition of CD44 expression. The results indicate that F9 selectively decreases the CD44 mediated binding of PBL to HUVEC.26

Debridement

Bromelain applied topically as a cream (35% bromelain in a lipid base) can be beneficial in the elimination of burn debris and in acceleration of healing. A non-proteolytic component of bromelain is responsible for this effect. This component, referred to as escharase, has no hydrolytic enzyme activity against normal protein substrates or various glycosaminoglycan substrates and its activity varies greatly from preparation to preparation.27

Topical bromelain has achieved complete debridement on experimental burns in rats in an average of 1.9 days as compared to collagenase, which required an average of 10.6 days for similar results.28

Topical bromelain separates eschar at the interface with living tissue. It is hypothesized that bromelain activates collagenase in living tissue which then attacks the denatured collagen in the eschar. This produces a demarcation between living and dead tissue. With very little scraping, using a tongue depressor, all of the eschar can be removed and a bed suitable for grafting results. By using bromelain, grafting can occur as soon as 24 hours after the accident. Utilizing bromelain cream in the treatment of burns usually results in minimal or no scar tissue formation.

The applicability of topical bromelain in frostbite eschar removal was extrapolated and investigated. In the initial trial, no debridement other than that of the superficial layers of the eschar was noted. Although third degree burn injuries debrided to a graftable bed after two topical applications of bromelain, frostbite injuries remained unaffected.29

Potentiation of Antibiotics

Antibiotic potentiation is one of the primary uses of bromelain in several foreign countries. Bromelain can modify the permeability of organs and tissues to different drugs. It prolongs sleeping time in mice administered pentobarbital30 and increases spinal levels of penicillin and gentamycin in rats. In humans, bromelain has been documented to increase blood and urine levels of antibiotics16 and results in higher blood and tissue levels of tetracycline and amoxycillin when they are administered concurrently with bromelain.31

Treatment of 18 women with 80 mg of bromelain concurrently with amoxycillin or tetracyclin resulted in increased serum levels and concentrations of both antibiotics in uterus, ovarian tubes, and ovaries as compared with controls. This effect was not generated by indomethacin, an anti-inflammatory drug which acts as a cyclooxygenase inhibitor, which indicates that bromelain has some undetermined activity that enhances absorption and tissue distribution of antibiotics.32 A three-fold increase in the level of tetracycline in serum after oral ingestion of 540 mg of enterically-coated bromelain has also been demonstrated in a double blind test.33

Combined bromelain and antibiotic therapy was instituted for 53 hospitalized patients with the following conditions; pneumonia, bronchitis, cutaneous staphylococcus infection, thrombophlebitis, cellulitis, pyelonephritis and perirectal and rectal abscesses. Twenty three of the patients had been on antibiotic therapy without success. Bromelain was administered four times a day along with the following antibiotics either alone or in combination; penicillin, chloramphenicol, erythromycin or novobiacin. A control group of 56 patients was treated with antibiotics alone. Of the 23 patients who had been unsuccessfully treated with antibiotics, 22 responded favorably to the combined treatment. In every disease state studied there was a significant reduction in morbidity when the combination of bromelain and antibiotics was used as opposed to antibiotics alone. Another group of 106 cases was treated with bromelain alone, with results comparable to those obtained with antibiotic treatment.34

Forty eight patients with acute sinusitis were placed on standard therapy, which included antihistamines and analgesic agents, along with antibiotics if indicated. Twenty three of the patients received bromelain four times daily, while the remaining 25 received a placebo. Of the patients receiving bromelain, 83% had complete resolution of nasal mucosal inflammation compared with only 52% in the placebo group. Improvement in breathing occurred in 78% of those receiving bromelain as compared to 68% in those receiving placebo. In the patients not receiving antibiotic treatment, 85% of patients receiving bromelain had complete resolution of inflammation of the nasal mucosa and complete resolution of breathing difficulties. Only 40% of the placebo group had a similar outcome with respect to inflammation, while 53% reported resolution of breathing difficulty.35

The potentiation of antibiotics and other medicines by bromelain may be due to enhanced absorption, as well as increased permeability of the diseased tissue which enhances the access of the antibiotic to the site of the infection. It is also thought that the use of bromelain may provide a similar access to specific and non-specific components of the immune system, therefore, enhancing the body’s utilization of its own healing resources.

Mucolytic Properties

The topical use of the enzymes, bromelain or papain, to remove excessive cervical mucus was demonstrated in 1954. Observations following its use demonstrated that pseudo and actual space-occupying lesions could be more positively identified, and inflammatory changes of the canal and its glands could be visualized with greater accuracy.36

Effects of bromelain on rabbit sputum consistency were investigated in vitro and in vivo. Of the enzymes tested, bromelain exerted the most potent lowering effect on sputum viscosity and also showed a tendency to increase the sputum volume.37

In a clinical study of 124 patients hospitalized with chronic bronchitis, pneumonia or bronchopneumonia, bronchiectasis, or pulmonary abscess, those receiving bromelain orally showed a decrease in the volume and purulence of the sputum.17 These results support the effectiveness of bromelain in decreasing the viscosity of sputum so that it can be more easily cleared from the respiratory tract.

Digestive Aid

Bromelain has been used successfully as a digestive enzyme following pancreatectomy, in cases of exocrine pancreas insufficiency and in other intestinal disorders.38 Because of its wide pH range, bromelain has activity in the stomach as well as the small intestine. It has also been shown to be an adequate replacement for pepsin and trypsin in cases of deficiency. The combination of ox bile, pancreatin and bromelain is effective in lowering stool fat excretion in patients with pancreatic steatorrhoea. In addition, this combination resulted in a gain in weight in most cases as well as an enhanced subjective feeling of well being. Symptomatic improvement was also noted in relation to pain, flatulence and stool frequency.39

Bromelain has been reported to heal gastric ulcers in experimental animals.40 In an extensive study of the effect of bromelain on the gastric mucosa, it was found that bromelain increased the uptake of radioactive sulfur by 50% and glucosamine by 30 -90%. Increased uptake of these substances may allow the gastric mucosa to heal more rapidly under the influence of bromelain.41

In a study designed to examine the effect of bromelain on enterotoxin receptor activity in porcine small intestine, orally administered bromelain inhibited enterotoxin attachment to pig small intestine in a dose-dependent manner. Attachment was negligible after treatment. Serum biochemical analysis and histopathological examination of treated piglets showed no adverse effects with the bromelain treatment. Administration of bromelain may therefore be useful for preventing enterotoxin-induced diarrhea.42

Surgical Procedures and Musculoskeletal Injuries

Bromelain also has therapeutic effects in the treatment of inflammation and soft tissue injuries. An early clinical trial on bromelain was conducted on 74 boxers with bruises on the face and haematomas of the orbits, lips, ears, chest and arms. Bromelain was given four times a day for 4 days or until all signs of bruising had disappeared. A control group of 72 boxers were given a placebo. In 58 of the boxers taking bromelain, all signs of bruising cleared completely in four days, with the remaining 16 requiring 8-10 days for complete clearance. In the control group, only 10 had complete clearance within four days, with the remainder requiring seven to fourteen days for resolution.43

The edema-reducing property of bromelain was investigated in traumatically-induced hindleg edema in rats. After enteral application of bromelain a significant reduction of the edema could be observed, however, parenteral application only resulted in a minimal therapeutic effect. Although enterally-applied enzymes are thought to be degraded in the gut, the better results were obtained after oral administration of bromelain, supporting the observation that bromelain can be absorbed by the gut without losing its biological properties.11

Fifty-five pre-surgical patients were divided into two groups. Group one, consisting of 22 patients, took bromelain four times a day for 48-72 hours prior to surgery and continued for 72 hours after surgery. Group two, consisting of 33 patients, took bromelain starting on the day of surgery, with the first dose administered one hour prior to surgery. Fifty percent of group one and 42.4% of group two had complete disappearance of pain and inflammation within 72 hours. Pain and inflammation persisted past 72 hours in only one member of the group supplemented with bromelain for three days prior to surgery, as opposed to five members of the group that started supplementation one hour prior to surgery. In a separate study, supplementation of bromelain starting 48-72 hours prior to surgery reduced the average number of days for complete disappearance of pain from 3.5 to 1.5, and disappearance of inflammation from 6.9 to 2.0 days, as compared with controls receiving no bromelain.44

Sixteen patients undergoing oral surgery were given bromelain four times a day starting 72 hours prior to surgery. At 24 hours after surgery, 75% of these patients were evaluated as having mild or no inflammation, in contrast to only 19% of a group receiving a placebo. Twenty-four hours after surgery, pain was either absent or mild in 38% of bromelain-treated patients, as opposed to 13% receiving placebo. After 72 hours, this increased to 75% of those in the bromelain group, as compared to only 38% in the placebo group.45

In an observation study involving 59 patients with blunt injuries to the musculoskeletal system, the efficacy and tolerability of high-dose bromelain, in addition to the usual therapeutic measures, was investigated. Treatment with bromelain resulted in a clear reduction in all four parameters tested; swelling, pain at rest and during movement, and tenderness.46

Cardiovascular and Circulatory Applications

Research has indicated that bromelain prevents aggregation of human blood platelets in vivo and in vitro, prevents or minimizes the severity of angina pectoris and transcient ischemic attacks (TIA), is useful in the prevention and treatment of thrombosis and thrombophlebitis, may break down cholesterol plaques, and exerts a potent fibrinolytic activity. If administered for prolonged time periods, bromelain also exerts an anti-hypertensive effect in experimental animals.2,47

Administration of 400-1000 mg/day of bromelain to 14 patients with angina pectoris resulted in the disappearance of symptoms in all patients within 4 to 90 days.48 Similar results have been observed in patients taking between 500-700 mg/day of bromelain. After discontinuing bromelain, angina attacks reappear after a variable period of time, often triggered by stressful experiences.2

A drastic reduction in the incidence of coronary infarct after administration of potassium and magnesium orotate along with 120-400 mg of bromelain per day has also been reported.49

In a study involving 73 patients with acute thrombophlebitis, bromelain, in addition to analgesics, was shown to decrease all symptoms of inflammation; including, pain, edema, tenderness, skin temperature, and disability.40

The ability of bromelain to influence these conditions may be due to its ability to breakdown fibrinous plaques. Bromelain has been shown to dissolve arteriosclerotic plaque in rabbit aorta in vivo and in vitro.2 It is likely that bromelain also increases vessel wall permeability to oxygen and nutrients while increasing blood fluidity, both of which aid in these conditions.

Toxicity, Side Effects and Allergic Reactions

Bromelain is considered to have very low toxicity, with an LD50 greater than 10g/kg. Toxicity tests on dogs, with increasing levels of bromelain up to 750 mg/kg administered daily, showed no toxic effects after six months. Dosages of1.5 g/kg/day administered to rats show no carcinogenic or teratogenic effects. 51

In human clinical tests, side effects have not been observed. Bromelain supplementation up to 460 mg has been shown to have no effect on heart rate or blood pressure; however, increasing doses up to 1840 mg have been shown to increase the heart rate proportionately. In some cases an increase of up to 80% of the baseline has been reported, which may be a result of bromelain’s influence on IL-1 and TNF production. Maximum effects were seen at 2 hours but some residual effect remained at 24 hours. At doses above 700 mg, palpitations and subjective discomfort have been reported. Blood pressure changes have not been demonstrated in humans at any dosage level.52

The allergenic potential of proteolytic enzymes should not be underestimated, for they cause, in particular, IgE-mediated respiratory allergies of both the immediate type and the late-phase of immediate type with predominantly respiratory symptoms. Allergy to bromelain has been reported in workers of a blood-grouping laboratory, and investigation indicates that (1) bromelain is a strong sensitizer, (2) sensitization usually occurs due to inhalation and not to ingestion, (3) bromelain allergy is occupationally acquired, and adequate precautions are necessary.53 The risk of sensitization to enzymes due to inhalation as a result of occupational exposure is very high (up to 50%).54

Bromelain has been shown to cross-react with the sera in about 28% of persons with IgE allergic response to honeybee venom.55 Bromelain, along with horseradish peroxidase and ascorbate oxidase are recognized by the IgE of sera from patients who are hypersensitive to olive tree pollen.56

Bromelain and papain, due to their use as a meat tenderizer and to clarify beer, are considered as potential ingestive allergens and may represent an unrecognized cause of an allergic reaction following a meal. As with other food substances, a small segment of the population, particularly those with a sensitivity to pineapple, may be sensitive to oral supplementation with bromelain. As contact allergens, the enzymes play a minor role; however, it is thought that skin testing with isolated proteases like bromelain may induce systemic reactions in susceptible individuals, even at very high dilution.53,57

Indications for the Use of Bromelain

There are several compelling reasons for supplementation with oral bromelain.

1. It inhibits blood platelet aggregation, favorably modulates prostaglandin formation and minimizes risk of coronary atherosclerotic disease.

2. It continues to provide a desired physiological action for as long as it is administered, with no evidence indicating that a tolerance develops.

3. It is considered to be non-toxic and lacking in side effects, so it can be used without concern in doses from 200 to 2000 mg for prolonged periods of time.

4. It is a protein and seems to be as easily metabolized as other dietary proteins.

5. It is well absorbed and seems to have greater therapeutic impact when administered orally as opposed to intravenously

6. While effective for inflammation and injury, it is even more effective if administered prior to a traumatic event, i.e. surgery or athletic competition.

7. It seems to enhance the absorption of and improve the action of other substances when they are administered in combination.

8. Because of its impact on the cytokine system, particularly IL-1 and TNF, which stimulate fever and acute phase response, and its demonstrated ability to increase the heart rate, bromelain may assist in generating an acute-stage healing response.

Bromelain has a wide range of conditions for which it has well documented therapeutic efficacy (see Table 4).

Dosage and Prescription Instructions

Available research does not demonstrate an enhanced efficacy of bromelain when it is administered between meals. It is generally recommended that bromelain be taken away from food unless it is being used as a digestive aid, because it is believed that otherwise, it will tend to act as a digestive enzyme and its therapeutic benefit may be diminished. While this may in fact be the case, the clinical studies conducted on bromelain have not followed this protocol.

Bromelain has shown therapeutic benefits in doses as small as 160 mg/day; however, it is thought that, for most conditions, best results occur starting at a dose of 750-1000 mg/day. Most research on bromelain has been done utilizing divided doses, usually four per day, and findings indicate that results are dose-dependent. See Table 5 for a summary of prescription instructions.

Conclusion

Bromelain has been used for a variety of clinical applications for more than 35 years. Although its mechanisms of action has not been completed resolved, bromelain has demonstrated a beneficial effect on the kinin system, the coagulation cascade, the cytokine system, and prostaglandin synthesis. Bromelain is believed to enhance the absorption of flavonoids and has been shown to increase absorption of glucosamine, so bromelain supplemention should be considered when these nutrients are given. It may also enhance absorption and utilization of many other substances; however, to date research in this area has focused primarily on antibiotics. Bromelain has been shown to exert a beneficial effect at doses as low as 160 mg/day, however, there is a general consensus among researchers that the best results occur when bromelain is given in doses above 500 mg per day and that results improve in a dose-dependent manner with higher levels of bromelain supplementation. Bromelain has been demonstrated to be well absorbed after an oral dose and has been shown to be safe at high doses for prolonged periods of time. For the conditions discussed in this review, bromelain has shown itself to be an effective supplement.”

PEACE.
MG

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Day 1

Squat
Incline Bench
Bent Row
Overhead Press
Barbell Curl

Day 2

Deadlift
Bench Press
Pulldown
D Press
D Curl

You can do calf and ab work on any day you feel like.

Do on Mon – Thurs or Sun – Wed just allow 2 full days of rest between workouts or even 3 if needed. Gauge yourself.

2 warm up sets followed by a set of 3-5 and then a set of 9-11.
Both sets taken to positive failure.

I know beginners are always looking for the magic bullet but this is your yellow brick road. Give this a year or 2 and size will be yours.

The secret is out now bust ASS!

RC

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Well, there is so much to the shitload that I can’t possibly cover it all in this post but I will touch on some of the basics.

The shitload will only work if you are lean enough, have your water correct, and are glycogen depleted enough. Of course, all three should be done whether you shitload or not but it gets funny when someone who wasn’t lean enough blames something like a shitload for making them look fat. lol I won’t mention any names but I should.

I have pretty much narrowed the shitload time down to 2 main options for 95% of guys who will use it successfully.

Friday night start shitloading.

Saturday morning start shitloading.

I use it starting friday night. This allows me to force alot of food without worrying about distention the next day. I recommend this for anyone that has a propensity towards distention – similar to the rounding out of the abs like Ronnie. Alot of food does this to me. When coming into the morning of the show, you have to be somewhat careful in your portion sizes. This is easier said than done simply because your body will continue to suck up most anything you put in your gut and continue to fill you out making you look better with every bite – literally. This tends to cause guys to continue to push the food. Also, if you are depleted as you should be, it is almost IMPOSSIBLE to start a shitload on friday night, continue into and through Saturday and take in too many carbs. It simply won’t happen.

Now, the guys that use the shitload on saturday are usually the ones that can’t get the idea of the excess sodium out of there heads and don’t want to ‘risk it’ by taking in large amounts of sodium the night before the show. If this is the case, do your homework. Sodium, in the absence of carbs and water (cause you are water restricted well before friday night), will NOT cause you to hold water subq. The carbs themselves are going to be scavenging for the last little bit of water in the body that it can get ahold of to combine with the carbs to form glycogen. Where you think that water is coming from? You guessed it – subq. So, you have restricted your water, added a ton of carbs that will suck water also, and are using atleast a mild diuretic. How the hell is sodium going to cause you to all of a sudden hold water subq? The sodium will not have enough time to shift the water before you hit the stage. Hell, most all of guys I have done this with have not started to smooth out until WELL into Sunday and most report still looking unbelievable on Sunday night. Remember, the excess sodium is also going to cause you be vascular as hell. The increase in blood pressure alone will cause this. I take 1/2 tsp. salt with a small amount of grape juice before hitting the stage. I have not used anything yet that can mimic the affect of vascularity as this compo does. Now, I do have 3 bottles of AMP this year but that is a different thread.hehe

Water restriction should remain the same as it would if you were carbing with a traditional carb load. The timing should stay the same. Same with diuretic use. I can’t think of anything that is any different off of the top of my low carb head. Even depletion workouts are the same. Yes, it is a bit harder to deplete and end the workouts on Wednesday and not load until friday night but, hey, we all pay a price. I increase dietary fats to keep the bodyweight from plummeting and it has worked very well.

You MUST do a trial run at about 4 or 5 weeks out to see how your body reacts. Of course, you need to be lean enough to get a good read. I have used the shitload trial run as early as 1 or 2 weeks out with great success. Make sure you are plenty depleted, though, or the affect will not be as pronounced.

Also, a traditional carb load is founded on filling out the muscles close to their ‘fullness’ or filling them up quite a bit. The shitload does not go along these same lines. With the shitload, you are looking for a very fast increase in the size of the muscle to make it tight enough to push hard against the skin and increase vascularity. You don’t have to be 90% full to hit the stage looking your best. In fact, if you are that full you will lose separation anyway – sort of ‘filling in the cracks’ if you will. I want my
cracks. lol

Slin isn’t any different either. This is where my argument about slin and fat intake began. I used slin every time I shitloaded before my last show. I loaded 5 times and used slin every time. I did nothing but get leaner. There was no extra fat storage or anything even remotely close to this. I loaded and recommend loading on things like Krispy Kremes, heavy fat and sugar type cookies like Mrs. Fields, rice krispy treats, caramel brownies (to die for), etc.. I am a bit leary of only one thing and that is dairy. I can’t say it is because I used dairy products and they didn’t work but milk based products would only seem to get in the way of your uptake of nutrients in the intestines, anyway. I don’t think they are a good idea but that is just me being cautious. They may work well – I just don’t know.

A few last notes:
If you already have a prep that dials you in perfectly, you would be a fool to change it. This type of prep is for the other 95% of guys that look twice as big and twice as hard on Sunday morning. I wonder why they look better on sunday morning after all of that pizza (a bit of sodium, ya think?), burgers, cheesecake and ice cream? Or why Chad Nichols’ boys walk around with peanut butter cups, jelly beans and peanut butter backstage? Or why Michael Ergas (with Chad when he won and got his pro card last year) was reportedly seen at a Wendy’s eating cheeseburgers like they were M & Ms?

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This post is just a simple guide for first time insulin users to follow in a safe, and effective manner.

I urge you to invest in a glucometer. This will give you a close estimation of where your BG(Blood Glucose) levels are (Safe Zone 70-90,but independent upon each individual).You want to take in adequate amounts of carbs, but not too much. As the excess will be stored as fat. And yes, if you aren’t careful, you can add quite a bit of excess body fat. As you’ll see in my dosing example below, we drop carbs slightly as to not to acquire excess BF.

As you already might know. The basic rule is 10g Dextrose to 1 iu of Insulin. Now the trick is to get in tune with your body so to take advantage of the insulin spike, which allows nutrients to be shuttled to the muscle cells rapidly, doing so without taking in excess carbs which equates to body fat.

Below is a 30 day cycle(which is recommended) for Insulin. I don’t use Insulin on off days from the gym. Some like to use Insulin on off days in the morning to fight off the catabolic state we’re in upon awakening. I feel upon awakening in the morning a shake consisting of Whey/Dextrose would be sufficient in bringing you out of this catabolic state from fasting over an 8 hour period while sleeping. Remember, you can become Insulin insensitive if abused. So by running slin on training days only reduces that threat.

I’ll use the 5 day training split as an example here. That will give you 20 days “on” slin.

Day 1 : 5 iu slin/50g Dextrose

Day 2 : 5 iu slin/50g Dextrose

Day 3 : 5 iu slin/50g Dextrose

Congratulations!! You’ve survived thus far. I assume(hope) you’ve been monitoring your BG levels. You probably have noticed that you are in the higher range using 50g of dextrose PWO. Now it’s time to drop the carbs slightly. Don’t fret. This should be more than ample amounts(of carbs) to get you through to your PPWO meal.

Day 4 : 5 iu slin/40g Dextrose

Day 5 : 5 iu slin/40g Dextrose

At this point you should have a good idea of how you react with Insulin in terms of BG levels vs. carb intake .

Let’s up the dose……

Day 6 : 6 iu slin/50g Dextrose

Day 7 : 6 iu slin/50g Dextrose

By this point in time you should be feeling good(ie;more confident),but still respectful to Insulin. Let’s test the waters for 3 days to give you the feel of things. By that I mean we’ll drop the carb intake slightly so you can find a comfortable ratio in regards to iu’s vs. carbs per gram.

Day 8 : 6 iu slin/40g Dextrose

Day 9 : 6 iu slin/40g Dextrose

Day 10 : 6 iu slin/40g Dextrose

Now, the above ratio’s are safe and effective. You can stop right here and continue on for the next 10 days at the above doses/ratio’s. Or you can move forward slightly.

Day 11 : 7 iu slin/50g Dextrose

Day 12 : 7 iu slin/50g Dextrose

Day 13 : 7 iu slin/50g Dextrose

Day 14 : 7 iu slin/50g Dextrose

Day 15 : & iu slin/50g Dextrose

If you felt confident with the above protocol.You could experiment on days 14-15 and drop your dextrose to 40g.If you do so, please monitor your BG levels every 15 minutes or so. And have glucose tabs, or another source of quick carbs handy (like orange juice) to stave off any possible signs of hypoglycemia. Don’t panic should this happen,just drink a glass of orange juice, or similar, and in 10 minutes the symptoms will have subsided.

Ok, on to your final week.

Day 16 : 8 iu slin/60g Dextrose

Day 17 : 8 iu slin/60g Dextrose

Day 18 : 8 iu slin/60g Dextrose

Day 19 : 8 iu slin/60g Dextrose

Day 20 : 8 iu slin/60g Dextrose

Congratulations! You just completed your first cycle/experience with Insulin in a safe an effective manner. I stopped at 8 iu’s, Being that is enough to get your feet wet with the drug. You can experiment later on. This was simply a guide.

One last thing. Guys ask “Which way is better?” To take your Whey/Dextrose in one shake, or Dextrose first, and whey 15 minutes later”?

Bottom line is, it’s just preference.

***All Veteran Insulin users,please feel free to add to this****

~Pinnacle~

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